Product Name | HPLC | Functions | Applications |
Glutathione | ≥98% | Detoxification;Anti-oxidant;Protect liver;Enhance immunity | Functional health;Dietary Supplements |
Structure
CAS Molecular Weight Molecular Formula Appearance
70-18-8 307.3 C10H17N3O6S White to off-white crystalline powder
Product Information
Reduced glutathione is a natural tripeptide composed of glutamic acid, cysteine and glycine. This ingredient is present in human cells and plays a crucial role in metabolic regulation. The reduced glutathione is known for its ability to activate multiple enzymes and promote the metabolism of carbohydrates, fats and proteins. Its detoxification, anti-oxidation and immune enhancing effects are widely recognized and utilized in a variety of healthcare products.
Mechanism
ROS can cause tissue fibrosis by acceler-ating abnormal proliferation of malondial-dehyde (MDA) and 4-hydroxynonenal(HNE). GSH can prevent tissue fibrosis byeliminating ROS.
ROS will affect lipid homeostasis regulation, block fatty acid oxidation, and cause lipid peroxidation. GSH can prevent lipid peroxidation by eliminating ROS.
ROS can stimulate the production of inflammatory factors, leading to inflamma-tion. GSH can achieve an anti-inflammato ry effect by eliminating ROS.
ROS can activate tyrosinase, leading to the production of melanin and causing skin hyperpigmentation. GSH can brighten the skin by eliminating ROS.
Efficacy
Fifteen patients with non-alcoholic fatty liver disease were supplemented with 300 mg/day of glutathione for 4 months. A decrease in plasma alanine transaminase (ALT) level was observed after 4 months.
Fifteen HIV-positive patients were randomly divided into two groups. One group was supplemented with glutathione (1260 mg/day). After 13 weeks, the group showed a significant decrease in inflammation factor (IL-6).
60 healthy people were orally administered with glutathione at a dose of 500 mg/day. After 4 weeks, the average melanin index of 6 parts is significantly decreased compared with the control group.
